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The phrase "be in charge of something" implies a position of responsibility or authority over a particular task, project, or area. When someone is in charge, they are typically responsible for overseeing, managing, or coordinating the activities related to that specific matter. This connects closely with the meaning of "kierować czymś," which translates to managing or directing something in Polish.

In contrast, the other options refer to situations that do not involve management or authority. "Być bez pracy" means to be unemployed, which doesn't imply any responsibility. "Być na zwolnieniu lekarskim" translates to being on sick leave, which also does not relate to a position of authority or control. Lastly, "otrzymać propozycję pracy" means to receive a job offer, which, while related to employment, does not indicate an active role of managing or leading. Thus, the correct answer encapsulates the concept of overseeing and guiding activities within a certain scope.